Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 19/20 | 0.44 |
| ▸ | ADRA1A | P35348 | 19/20 | 0.44 |
| ▸ | ADRA1B | P35368 | 19/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | HRH1 | P35367 | 2/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.36 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.36 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6965725 | 0.88 | ADRA1D (0.44) | ADRA1DADRA1AADRA1B | |
| SCHEMBL8138891 | 0.77 | ADRA1D (0.42) | ADRA1DADRA1AADRA1BHRH1 | |
| Hydrochloric Acid SCHEMBL8018795 | 0.76 | ADRA1A (0.47) | ADRA1DADRA1AADRA1BMEN1KMT2A | |
| SCHEMBL7217049 | 0.74 | ADRA1D (0.51) | ADRA1DADRA1AADRA1BHRH1 | |
| SCHEMBL7954991 | 0.73 | ADRA1D (0.39) | ADRA1DADRA1AADRA1B | |
| SCHEMBL7954985 | 0.73 | ADRA1D (0.39) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL8014302 | 0.72 | ADRA1A (0.46) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| Trifluoroacetic Acid SCHEMBL7967514 | 0.72 | ADRA1D (0.38) | ADRA1DADRA1AADRA1B | |
| Hydrochloric Acid SCHEMBL7141675 | 0.71 | ADRA1A (0.55) | ADRA1DADRA1AADRA1BHRH1ADRA2A | |
| SCHEMBL7968309 | 0.71 | ADRA1D (0.40) | ADRA1DADRA1AADRA1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6080760-A | TREATING BENIGN PROSTATIC HYPERPLASIA; COMPLEMENT SLOWER-ACTING THERAPEUTICS BY PROVIDING ACUTE RELIEF; INDUCE RELAXATION OF THE LOWER URINARY TRACT TO DECREASE DIFFICULTY IN URINATION AND SEXUAL DYSFUNCTION | MERCK & CO., INC. (US) | 2000-06-27 | — | — | US | disclosed |