Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 3/20 | 0.47 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.47 |
| ▸ | GPR3 | P46089 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | PDE2A | O00408 | 1/20 | 0.40 |
| ▸ | NISCH | Q9Y2I1 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14743240 | 0.93 | TRPV1 (0.53) | TRPV1MAPTEPHX2GPR3L3MBTL1 | |
| SCHEMBL254957 | 0.86 | MAPT (0.56) | TRPV1MAPTEPHX2GPR3L3MBTL1 | |
| SCHEMBL1259588 | 0.80 | TRPV1 (0.42) | TRPV1MAPTEPHX2APPCA1 | |
| SCHEMBL25291993 | 0.80 | ALDH1A1 (0.46) | TRPV1KIF11APPALDH1A1TSHR | |
| SCHEMBL20380903 | 0.79 | MAPT (0.47) | TRPV1MAPTEPHX2GPR3L3MBTL1 | |
| SCHEMBL2836246 | 0.78 | TRPV1 (0.45) | TRPV1MAPTEPHX2APPALDH1A1 | |
| SCHEMBL28780452 | 0.78 | EPHX2 (0.50) | MAPTEPHX2GPR3L3MBTL1KDM4E | |
| SCHEMBL1258083 | 0.77 | TRPV1 (0.40) | TRPV1APPCA1CA2CA9 | |
| SCHEMBL13863723 | 0.76 | MAPT (0.48) | TRPV1MAPTEPHX2GPR3L3MBTL1 | |
| SCHEMBL255560 | 0.76 | GPR3 (0.52) | MAPTEPHX2GPR3L3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 899 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117586274-B | Forskolin ring-expanding derivative and preparation method and application thereof | 南通大学附属医院 | 2025-04-01 | — | — | CN | claimed |
| CN-119462748-A | Preparation method of fluorine-containing carbazole phosphonic acid compound | 浙江科技大学 | 2025-02-18 | — | — | CN | claimed |
| CN-117362310-B | Forskolin oxygen bridged ring derivative and preparation method thereof | 南通大学 | 2024-12-06 | — | — | CN | claimed |
| CN-117586274-A | Forskolin ring-expanding derivative and preparation method and application thereof | 南通大学附属医院 | 2024-02-23 | — | — | CN | claimed |
| CN-117362310-A | Forskolin oxygen bridged ring derivative and preparation method thereof | 南通大学 | 2024-01-09 | — | — | CN | claimed |
| CN-117304202-A | Foscow Lin Fangting derivative and preparation method and application thereof | 南通大学 | 2023-12-29 | — | — | CN | claimed |
| CN-108059606-B | Method for preparing metaflumizone intermediate by using urea | 扬州工业职业技术学院 | 2020-03-27 | — | — | CN | claimed |
| CN-108129358-B | Clean and efficient metaflumizone synthesis process | 扬州工业职业技术学院 | 2020-03-24 | — | — | CN | claimed |
| CN-107188841-B | A kind of synthetic method of asymmetry diaryl list selenide compound | 温州医科大学 | 2019-07-16 | — | — | CN | claimed |
| CN-108129358-A | A kind of metaflumizone synthesis technology of clean and effective | 扬州工业职业技术学院 | 2018-06-08 | — | — | CN | claimed |
| CN-108059606-A | A kind of method that metaflumizone intermediate is prepared using urea | 扬州工业职业技术学院 | 2018-05-22 | — | — | CN | claimed |
| EP-1963344-A1 | ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS | UNIVERSITEIT GENT (BE) | 2008-09-03 | — | — | EP | claimed |
| WO-2007071453-A1 | ORGANOPHOSPHORIC DERIVATIVES USEFUL AS ANTI-PARASITIC AGENTS | UNIVERSITEIT GENT (BE) | 2007-06-28 | — | — | WO | claimed |
| EP-0335541-B1 | ANTIPARASITIC AVERMECTIN DERIVATIVES | Pfizer Limited (GB) | 1992-07-22 | — | — | EP | claimed |
| EP-0335541-A2 | Antiparasitic avermectin derivatives | Pfizer Limited (GB) | 1989-10-04 | — | — | EP | claimed |
| US-20260070945-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL-MYERS SQUIBB COMPANY | 2026-03-12 | — | — | US | disclosed |
| US-20260022142-A1 | MACROCYCLIC IMMUNOMODULATORS | BRISTOL MYERS SQUIBB CO (US) | 2026-01-22 | — | — | US | disclosed |
| EP-0109606-B1 | PROCESS FOR THE FORMYLATION OF ARYL HALIDES | BAYER AG (DE) | 1986-01-22 | — | — | EP | disclosed |
| US-4536344-A | USING A PHOSPINE OR PHOSPHITE | BAYER AKTIENGESELLSCHAFT (DE) | 1985-08-20 | — | — | US | disclosed |
| EP-0109606-A1 | Process for the formylation of aryl halides | BAYER AG (DE) | 1984-05-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022142-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1LG2, PDCD1 | TRPV1 3935/4885MAPT 4702/4885EPHX2 4082/4885 |
| US-20260070945-A1 | MACROCYCLIC IMMUNOMODULATORS | CD274, PDCD1, PDCD1LG2 | TRPV1 3668/4885MAPT 4639/4885EPHX2 3786/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.