Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR3C1 | P04150 | 1/20 | 0.40 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 2/20 | 0.37 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8078157 | 0.88 | CES2 (0.37) | NR3C1AOC3LMNAALDH1A1BRD4 | |
| SCHEMBL8077592 | 0.85 | CES2 (0.44) | LMNABRD4CREBBPMAPTHDAC4 | |
| SCHEMBL8074863 | 0.84 | CES2 (0.44) | — | |
| SCHEMBL2755399 | 0.84 | LMNA (0.44) | LMNAMAPK1 | |
| SCHEMBL8064415 | 0.82 | CYP3A4 (0.42) | MAPT | |
| SCHEMBL8079476 | 0.80 | SLC6A4 (0.37) | — | |
| SCHEMBL8074559 | 0.79 | LMNA (0.35) | AOC3LMNAALDH1A1HTTKDM4E | |
| SCHEMBL8077682 | 0.78 | LMNA (0.41) | LMNAALDH1A1 | |
| SCHEMBL21831133 | 0.77 | F2RL1 (0.45) | AOC3LMNAALDH1A1BRD4CREBBP | |
| SCHEMBL30910896 | 0.77 | F2RL1 (0.45) | AOC3LMNAALDH1A1BRD4CREBBP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999045017-A1 | METHYL RED ENERGY TRANSFER REAGENT FOR DNA ANALYSIS | ASTRAZENECA UK LIMITED (GB) | 1999-09-10 | — | — | WO | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |