Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | DAO | P14920 | 1/20 | 0.32 |
| ▸ | AOC3 | Q16853 | 1/20 | 0.32 |
| ▸ | METAP2 | P50579 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8064216 | 0.79 | NR3C1 (0.40) | LMNAALDH1A1HTTMAPTKDM4E | |
| SCHEMBL4427290 | 0.76 | IDO1 (0.46) | LMNAALDH1A1SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL8024132 | 0.75 | ALOX15 (0.36) | LMNAMAPTALOX15SLC6A2SLC6A3 | |
| SCHEMBL3667517 | 0.74 | IDO1 (0.40) | LMNAHTTMAPTKDM4ETP53 | |
| SCHEMBL8078157 | 0.70 | CES2 (0.37) | LMNAALDH1A1ALOX15SLC6A2SLC6A4 | |
| SCHEMBL11436873 | 0.70 | ALOX15 (0.39) | ALDH1A1ALOX15MAPK1HSD17B10SLC6A4 | |
| SCHEMBL7081445 | 0.70 | LMNA (0.41) | LMNAALDH1A1HTTMAPTKDM4E | |
| SCHEMBL8064415 | 0.69 | CYP3A4 (0.42) | MAPTSLC6A2SLC6A4SLC6A3PKM | |
| SCHEMBL6816674 | 0.69 | F2 (0.34) | KDM4EALOX15MAPK1SLC6A4 | |
| SCHEMBL8077592 | 0.68 | CES2 (0.44) | LMNAMAPTSLC6A2SLC6A4MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |
| WO-1999034790-A1 | GLYCINE TRANSPORT INHIBITORS | ALLELIX NEUROSCIENCE, INC. (US) | 1999-07-15 | — | — | WO | disclosed |