Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CREB1 | P16220 | 6/20 | 0.83 |
| ▸ | FLT3 | P36888 | 3/20 | 0.83 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.83 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.83 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.83 |
| ▸ | SLCO2B1 | O94956 | 1/20 | 0.83 |
| ▸ | PTPRS | Q13332 | 2/20 | 0.79 |
| ▸ | ABCB1 | P08183 | 6/20 | 0.70 |
| ▸ | MAPT | P10636 | 5/20 | 0.70 |
| ▸ | ABCG2 | Q9UNQ0 | 3/20 | 0.70 |
| ▸ | NPC1 | O15118 | 3/20 | 0.70 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.70 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.70 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.70 |
| ▸ | TSHR | P16473 | 1/20 | 0.70 |
| ▸ | GABRP | O00591 | 3/20 | 0.68 |
| ▸ | GABRD | O14764 | 3/20 | 0.68 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.68 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.68 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.68 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17663637 | 0.91 | CREB1 (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Oroxylin A SCHEMBL431423 | 0.91 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Oroxylin A SCHEMBL30452350 | 0.91 | CREB1 (1.00) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL8063178 | 0.88 | FLT3 (0.83) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Baicalein Trimethyl Ether SCHEMBL971297 | 0.86 | ABCB1 (0.80) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL8064387 | 0.85 | KDM4E (0.83) | MAPTNPC1MEN1KMT2APOLB | |
| SCHEMBL30606765 | 0.85 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| SCHEMBL28660389 | 0.85 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Mosloflavone SCHEMBL971985 | 0.84 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 | |
| Mosloflavone SCHEMBL29477310 | 0.84 | KDM4E (0.81) | CREB1FLT3PRSS1PRSS2PRSS3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6025387-A | Gastroprotective flavone/flavanone compounds with therapeutic effect on inflammatory bowel disease | DONG A PHARMACEUTICAL CO., LTD. (KR) | 2000-02-15 | — | — | US | disclosed |
| EP-0915864-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | Dong A Pharmaceutical Co. Ltd. (KR) | 1999-05-19 | — | — | EP | disclosed |
| WO-1998004541-A1 | GASTROPROTECTIVE FLAVONE/FLAVANONE COMPOUNDS WITH THERAPEUTIC EFFECT ON INFLAMMATORY BOWEL DISEASE | DONG A PHARMACEUTICAL CO., LTD. (KR) | 1998-02-05 | — | — | WO | disclosed |