SCHEMBL8064299

SCHEMBL8064299

CCc1cc(OC(C)C)c(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 7/20 0.43
ABCB1 P08183 2/20 0.39
ABCC1 P33527 2/20 0.39
POLB P06746 2/20 0.37
KAT6A Q92794 1/20 0.37
CNR1 P21554 1/20 0.37
SFRP1 Q8N474 2/20 0.36
PSIP1 O75475 1/20 0.36
GAA P10253 1/20 0.36
GFER P55789 1/20 0.36
CNR2 P34972 1/20 0.35
MMP2 P08253 1/20 0.35
MMP8 P22894 1/20 0.35
MMP12 P39900 1/20 0.35
MMP13 P45452 1/20 0.35
MMP14 P50281 1/20 0.35
MMP16 P51512 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8061991 0.82 HTR6 (0.45) HTR6ABCB1ABCC1POLB
SCHEMBL8064343 0.82 HTR6 (0.45) HTR6ABCB1ABCC1POLBKAT6A
SCHEMBL8061986 0.78 HTR6 (0.46) HTR6ABCB1ABCC1POLBCNR1
SCHEMBL4028049 0.77 HTR6 (0.66) HTR6ABCB1ABCC1POLBCNR1
SCHEMBL8046743 0.74 POLB (0.56) HTR6POLBPSIP1GAAGFER
SCHEMBL8057519 0.74 ALDH1A1 (0.47) HTR6GAA
SCHEMBL10786726 0.72 POLB (0.53) HTR6POLBPSIP1GAAGFER
SCHEMBL8061999 0.71 ABCB1 (0.47) HTR6ABCB1ABCC1POLBCNR1
SCHEMBL10181290 0.69 HSD11B1 (0.59) HTR6PSIP1MMP2MMP8MMP12
SCHEMBL8059447 0.69 L3MBTL1 (0.54) POLBGAAGFER

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed