SCHEMBL8061986

SCHEMBL8061986

CC(C)Oc1ccc(S(=O)(=O)c2ccccc2)cc1S(=O)(=O)c1ccccc1

nearest known ligand 0.46

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 6/20 0.46
POLB P06746 3/20 0.44
ALDH1A1 P00352 2/20 0.44
SMN1; SMN2 Q16637 2/20 0.44
MAPT P10636 1/20 0.44
ABCB1 P08183 1/20 0.44
ABCC1 P33527 1/20 0.44
TSHR P16473 1/20 0.42
MAPK1 P28482 1/20 0.42
CNR1 P21554 1/20 0.41
SFRP1 Q8N474 2/20 0.40
L3MBTL1 Q9Y468 1/20 0.40
CNR2 P34972 2/20 0.40
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
HSD11B1 P28845 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8058766 0.88 GAA (0.50) POLBALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL8061999 0.87 ABCB1 (0.47) HTR6POLBALDH1A1SMN1; SMN2MAPT
SCHEMBL8064293 0.86 ALDH1A1 (0.48) HTR6POLBALDH1A1SMN1; SMN2MAPT
SCHEMBL8429001 0.86 ALDH1A1 (0.45) POLBALDH1A1SMN1; SMN2MAPTABCB1
SCHEMBL4028049 0.83 HTR6 (0.66) HTR6POLBALDH1A1ABCB1ABCC1
SCHEMBL8047043 0.83 KMT2A (0.56) POLBALDH1A1SMN1; SMN2MAPTTSHR
SCHEMBL8046997 0.82 HTR6 (0.69) HTR6POLBALDH1A1SMN1; SMN2MAPT
SCHEMBL8064343 0.80 HTR6 (0.45) HTR6POLBALDH1A1SMN1; SMN2MAPT
SCHEMBL8058697 0.78 HTR6 (0.46) HTR6POLBALDH1A1SMN1; SMN2MAPT
SCHEMBL8064299 0.78 HTR6 (0.43) HTR6POLBABCB1ABCC1CNR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US claimed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP claimed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP claimed
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed