SCHEMBL8064310

SCHEMBL8064310

Cc1ccc(S(=O)(=O)c2ccc(-c3ccc(C(=O)O)cc3)c(S(=O)(=O)c3ccc(C)cc3)c2)cc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
POLB P06746 5/20 0.57
ALDH1A1 P00352 3/20 0.56
HSD17B13 Q7Z5P4 1/20 0.52
L3MBTL1 Q9Y468 2/20 0.49
MEN1 O00255 1/20 0.49
MAPT P10636 1/20 0.49
APOBEC3A P31941 1/20 0.49
RECQL P46063 1/20 0.49
KMT2A Q03164 1/20 0.49
APOBEC3G Q9HC16 1/20 0.49
TDP1 Q9NUW8 1/20 0.49
TP53 P04637 1/20 0.49
SMN1; SMN2 Q16637 1/20 0.47
RXRA P19793 2/20 0.46
RXRB P28702 2/20 0.46
RXRG P48443 1/20 0.46
MAP4K4 O95819 1/20 0.45
GAA P10253 1/20 0.44
APEX1 P27695 1/20 0.44
CTDSP1 Q9GZU7 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8046836 0.88 ALDH1A1 (0.48) POLBALDH1A1HSD17B13L3MBTL1KMT2A
SCHEMBL8064351 0.87 HSD17B13 (0.46) POLBALDH1A1HSD17B13L3MBTL1MEN1
SCHEMBL8046887 0.86 ALDH1A1 (0.51) POLBALDH1A1L3MBTL1MEN1MAPT
SCHEMBL7316384 0.82 ALDH1A1 (0.71) POLBALDH1A1HSD17B13L3MBTL1MEN1
SCHEMBL8064306 0.77 ALDH1A1 (0.45) POLBALDH1A1L3MBTL1MEN1MAPT
SCHEMBL361052 0.77 CSNK2A2 (0.50) POLBALDH1A1L3MBTL1MEN1MAPT
SCHEMBL8057544 0.75 RXRA (0.52) ALDH1A1HSD17B13MEN1KMT2ARXRA
SCHEMBL19627078 0.75 ALDH1A1 (0.71) POLBALDH1A1MEN1MAPTKMT2A
SCHEMBL9852574 0.75 CA12 (0.70) POLBALDH1A1L3MBTL1MEN1KMT2A
SCHEMBL18833185 0.74 GAA (0.59) POLBALDH1A1HSD17B13L3MBTL1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6040470-A DERIVATIVES OF 1-ORGANOETHER,-ESTER OR SULFONE-2,4-BIS-PHENYLSULFONYL)BENZENE IN AN AQUEOUS DEVELOPER SLURRY TO PREVENT DETERIORATION OF DISPERSION DUE TO HYDRATION; HIGHLY SENSITIVE; LESS SURFACE BLUSHING; STORAGE STABILITY OF IMAGE SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 2000-03-21 US disclosed
EP-0791578-B1 Sulfonyl compound and thermalsensitive recording medium using the same SANKO KAIHATSU KAGAKU KENK (JP) 1999-11-10 EP disclosed
US-5840652-A HIGH SENSITIVITY, STORAGE STABILITY SANKO KAIHATSU KAGAKU KENKYUSHO (JP) 1998-11-24 US disclosed
EP-0791578-A2 Sulfonyl compound and thermalsensitive recording medium using the same Sanko Kaihatsu Kagaku Kenkyusho (JP) 1997-08-27 EP disclosed