Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | HTR7 | P34969 | 1/20 | 0.41 |
| ▸ | MMP1 | P03956 | 3/20 | 0.41 |
| ▸ | ADAM17 | P78536 | 1/20 | 0.41 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8062191 | 0.93 | RAB9A (0.49) | RAB9APAX8 | |
| SCHEMBL4535339 | 0.83 | ATM (0.47) | RAB9AHTR7PAX8 | |
| SCHEMBL8064689 | 0.81 | RAB9A (0.43) | RAB9APAX8NPC1 | |
| SCHEMBL4536842 | 0.80 | RAB9A (0.50) | RAB9ANPC1 | |
| SCHEMBL4541154 | 0.75 | RAB9A (0.56) | RAB9APAX8 | |
| SCHEMBL8064827 | 0.74 | TP53 (0.41) | RAB9APAX8 | |
| SCHEMBL4537510 | 0.74 | RAB9A (0.56) | RAB9AHTR7PAX8NPC1 | |
| SCHEMBL8069502 | 0.74 | RAB9A (0.50) | RAB9ANPC1 | |
| SCHEMBL4542461 | 0.74 | RAB9A (0.50) | RAB9ANPC1 | |
| SCHEMBL4538787 | 0.73 | PSEN1 (0.51) | PAX8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |