Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 3/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.48 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.47 |
| ▸ | MMP7 | P09237 | 1/20 | 0.47 |
| ▸ | MMP13 | P45452 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4537185 | 0.97 | RAB9A (0.56) | RAB9APAX8ALDH1A1LMNANPSR1 | |
| SCHEMBL8069502 | 0.87 | RAB9A (0.50) | RAB9ANPC1EPHX2EPHX1 | |
| SCHEMBL4537316 | 0.87 | LMNA (0.56) | RAB9APAX8LMNANPSR1EPHX2 | |
| SCHEMBL4542461 | 0.87 | RAB9A (0.50) | RAB9ANPC1EPHX2EPHX1 | |
| SCHEMBL4542345 | 0.87 | EPHX2 (0.56) | RAB9AEPHX2EPHX1 | |
| SCHEMBL4542837 | 0.87 | RAB9A (0.53) | RAB9APAX8LMNAEPHX2EPHX1 | |
| SCHEMBL4542205 | 0.87 | RAB9A (0.52) | RAB9APAX8NPC1HCRTR1HCRTR2 | |
| SCHEMBL4539998 | 0.85 | LMNA (0.55) | PAX8LMNANPSR1EPHX2EPHX1 | |
| SCHEMBL4534756 | 0.85 | RAB9A (0.49) | RAB9ANPC1EPHX2EPHX1 | |
| SCHEMBL4538117 | 0.84 | FKBP1A (0.48) | RAB9APAX8ALDH1A1LMNANPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |