Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BDKRB1 | P46663 | 13/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8069510 | 0.89 | BRD4 (0.53) | — | |
| SCHEMBL4530967 | 0.87 | HTR7 (0.48) | SMN1; SMN2 | |
| SCHEMBL4536848 | 0.86 | HTR1A (0.48) | — | |
| SCHEMBL4538141 | 0.86 | BDKRB1 (0.46) | BDKRB1KMT2A | |
| SCHEMBL8062041 | 0.86 | RAB9A (0.47) | — | |
| SCHEMBL4537565 | 0.86 | RAB9A (0.51) | — | |
| SCHEMBL4539543 | 0.85 | RAB9A (0.47) | POLBKMT2A | |
| SCHEMBL8064960 | 0.85 | EPHX2 (0.50) | BDKRB1POLBCNR1 | |
| SCHEMBL4539816 | 0.84 | RAB9A (0.60) | — | |
| SCHEMBL8049802 | 0.83 | KMT2A (0.52) | SMN1; SMN2CNR1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |