Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | RECQL | P46063 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | CDK2 | P24941 | 2/20 | 0.41 |
| ▸ | ADAMTS4 | O75173 | 1/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.41 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | MMP9 | P14780 | 1/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.41 |
| ▸ | CA6 | P23280 | 1/20 | 0.41 |
| ▸ | MMP12 | P39900 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | ADAMTS5 | Q9UNA0 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7091918 | 0.73 | TRPA1 (0.39) | ALDH1A1LMNAHPGDHSD17B10TDP1 | |
| SCHEMBL7089233 | 0.72 | SIGMAR1 (0.50) | ALDH1A1LMNAHPGDALOX15TDP1 | |
| SCHEMBL20408303 | 0.72 | SIGMAR1 (0.50) | ALDH1A1LMNAHPGDALOX15TDP1 | |
| SCHEMBL7089231 | 0.72 | SIGMAR1 (0.50) | ALDH1A1LMNAHPGDALOX15TDP1 | |
| SCHEMBL7089296 | 0.72 | CYP1A2 (0.50) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| SCHEMBL7089301 | 0.72 | CYP1A2 (0.50) | ALDH1A1HPGDALOX15HSD17B10TDP1 | |
| Pyrogallol SCHEMBL225781 | 0.71 | CA1 (0.71) | THRBALDH1A1LMNACA1CA2 | |
| SCHEMBL3078969 | 0.70 | LMNA (0.52) | ALDH1A1LMNACA1CA2RECQL | |
| SCHEMBL8060455 | 0.70 | MAPT (0.56) | THRBALDH1A1LMNACA1CA2 | |
| Pyrogallol SCHEMBL8433563 | 0.69 | CA1 (0.67) | THRBALDH1A1LMNACA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015851-A | MELT PROCESSABILITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0965612-A1 | Rubber compositions containig bis anil compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |