SCHEMBL8065181

SCHEMBL8065181

O=C(Cc1ccc(Br)cc1)Cc1ccc(Cl)c(Cl)c1

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MGAM O43451 1/20 0.48
GAA P10253 1/20 0.48
SI P14410 1/20 0.48
MGAM2 Q2M2H8 1/20 0.48
PTPRC P08575 1/20 0.48
PTPRG P23470 1/20 0.48
PIK3CA P42336 1/20 0.47
KMT2A Q03164 4/20 0.46
MEN1 O00255 3/20 0.46
TAOK1 Q7L7X3 1/20 0.46
TAOK3 Q9H2K8 1/20 0.46
LMNA P02545 1/20 0.45
HTT P42858 1/20 0.45
SMN1; SMN2 Q16637 1/20 0.45
POLB P06746 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MAPT P10636 1/20 0.44
GPR183 P32249 1/20 0.44
TSHR P16473 1/20 0.44
CA2 P00918 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7403121 0.84 SIGMAR1 (0.51) PTPRGPIK3CAKMT2AHTTCA2
SCHEMBL1449785 0.82 MEN1 (0.52) GAAKMT2AMEN1LMNAHTT
SCHEMBL1351021 0.81 PIK3CA (0.50) PIK3CAKMT2AMEN1LMNAHTT
SCHEMBL2251905 0.79 PIK3CA (0.51) PIK3CAKMT2AMEN1LMNAHTT
SCHEMBL8376663 0.78 TSHR (0.50) PIK3CAKMT2ASMN1; SMN2TSHRCA2
SCHEMBL823446 0.78 PNMT (0.52) PIK3CAKMT2AMEN1POLBHSP90AA1
SCHEMBL630988 0.77 PIK3CA (0.53) PIK3CAKMT2AMEN1LMNAHTT
SCHEMBL2432358 0.77 LMNA (0.48) GAAKMT2AMEN1LMNAHTT
Hydrochloric Acid SCHEMBL826127 0.76 PNMT (0.50) PIK3CAKMT2AMEN1POLBHSP90AA1
SCHEMBL14775643 0.76 VNN1 (0.49) PIK3CAKMT2AMEN1LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1003714-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES Hoechst Schering AgrEvo S.A. (FR) 2000-05-31 EP disclosed
WO-1999001422-A1 AROMATIC AMIDES, THEIR PREPARATION PROCESS AND THEIR USE AS PESTICIDES HOECHST SCHERING AGREVO S.A. (FR) 1999-01-14 WO disclosed