SCHEMBL8065249

SCHEMBL8065249

NC(=O)N1CCC(CCCC2CCN(C(N)=O)CC2)CC1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ITGB3 P05106 2/20 0.46
ITGA2B P08514 2/20 0.46
ALDH1A1 P00352 1/20 0.44
SLC18A3 Q16572 1/20 0.40
GNAI3 P08754 2/20 0.39
GNAO1 P09471 2/20 0.39
GNAI1 P63096 2/20 0.39
HDAC3 O15379 4/20 0.39
HDAC4 P56524 4/20 0.39
HDAC1 Q13547 4/20 0.39
HDAC7 Q8WUI4 4/20 0.39
HDAC2 Q92769 4/20 0.39
HDAC10 Q969S8 4/20 0.39
HDAC11 Q96DB2 4/20 0.39
HDAC8 Q9BY41 4/20 0.39
HDAC6 Q9UBN7 4/20 0.39
HDAC9 Q9UKV0 4/20 0.39
HDAC5 Q9UQL6 4/20 0.39
TPSAB1 Q15661 1/20 0.37
TPSD1 Q9BZJ3 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5810827 0.87 GNAI3 (0.51) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL1009220 0.85 CHRM2 (0.46) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL1515538 0.85 AKR1C3 (0.42) ITGB3ITGA2BGNAI3GNAO1GNAI1
SCHEMBL6062762 0.84 ITGB3 (0.36) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL19049588 0.84 ALDH1A1 (0.44) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL3121330 0.83 TPSAB1 (0.41) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL31510764 0.83 TPSAB1 (0.35) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL14814157 0.83 GNAI3 (0.44) ALDH1A1GNAI3GNAO1GNAI1TPSAB1
SCHEMBL30684623 0.82 ITGB3 (0.46) ITGB3ITGA2BALDH1A1GNAI3GNAO1
SCHEMBL4578235 0.80 ALOX5 (0.44) ITGB3ITGA2BTPSAB1TPSD1TPSG1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP claimed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP claimed
EP-0673782-B1 Recording sheets containing pyrrole, pyrrolidine, pyridine, piperidine, homopiperidine, quinoline, isoquinoline, quinuclidine, indole, and indazole compounds XEROX CORP (US) 2000-06-14 EP claimed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP claimed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US claimed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US claimed
EP-0743574-B1 Migration imaging members XEROX CORP (US) 2000-12-27 EP disclosed
EP-0743573-B1 Method for obtaining image contrast migration imaging members XEROX CORP (US) 2000-09-06 EP disclosed
EP-0684509-B1 Contrast-promoting agents in graphic arts media IMATION CORP (US) 1999-10-20 EP disclosed
EP-0743573-A2 Method for obtaining image contrast migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
EP-0743574-A2 Migration imaging members XEROX CORPORATION (US) 1996-11-20 EP disclosed
US-5563014-A SOFTENABLE LAYER CONTAINIG PHOTOSENSITIVE MARKING MATERIAL; TRANSPARENTIZING AGENT XEROX CORPORATION (US) 1996-10-08 US disclosed
US-5514505-A SELECTIVE TRANSPARENTIZATION OF PHOTOSENSITIVE MIGRATION MARKING PARTICLES EMBEDDED NEAR THE SURFACE OF A SOFTENABLE LAYER SUPPORTED BY AN ELECTROCONDUCTIVE SUBSTRATE XEROX CORPORATION (US) 1996-05-07 US disclosed
US-5494776-A CONTAINING 2,5-PIPERAZINEDIONE, GLYCOLURIL, GLUTARIMIDE OR 3-IMINOISOINDOLINONE COMPOUNDS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1996-02-27 US disclosed
EP-0684510-A1 Hybrid graphic arts films with reduced occurrence of pepper fog MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-29 EP disclosed
EP-0684509-A1 Contrast-promoting agents in graphic arts media MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-11-29 EP disclosed
US-5415975-A Contrast-promoting agents in graphic arts media MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-16 US disclosed