Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOS3 | P29474 | 4/20 | 0.65 |
| ▸ | NOS2 | P35228 | 4/20 | 0.65 |
| ▸ | CA12 | O43570 | 3/20 | 0.56 |
| ▸ | CA1 | P00915 | 3/20 | 0.56 |
| ▸ | CA2 | P00918 | 3/20 | 0.56 |
| ▸ | CA9 | Q16790 | 3/20 | 0.56 |
| ▸ | ESR2 | Q92731 | 6/20 | 0.54 |
| ▸ | ESR1 | P03372 | 5/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NOS1 | P29475 | 3/20 | 0.48 |
| ▸ | S100B | P04271 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | GMNN | O75496 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11311039 | 0.83 | NOS3 (0.65) | NOS3NOS2CA12CA1CA2 | |
| SCHEMBL14816923 | 0.78 | HTR3E (0.61) | NOS3NOS2ESR2NOS1MEN1 | |
| SCHEMBL9349552 | 0.77 | ESR2 (0.60) | NOS3NOS2CA12CA1CA2 | |
| SCHEMBL8197688 | 0.76 | HTR3E (0.58) | NOS3NOS2ESR2ESR1GAA | |
| SCHEMBL17471480 | 0.75 | NOS3 (0.56) | NOS3NOS2CA12CA1CA2 | |
| SCHEMBL2348627 | 0.74 | NOS1 (0.67) | NOS3NOS2ESR2ESR1NOS1 | |
| SCHEMBL165971 | 0.74 | NOS1 (0.67) | NOS3NOS2ESR2ESR1NOS1 | |
| SCHEMBL165970 | 0.74 | NOS1 (0.67) | NOS3NOS2ESR2ESR1NOS1 | |
| SCHEMBL6650679 | 0.72 | NOS1 (0.64) | NOS3NOS2ESR2ESR1NOS1 | |
| SCHEMBL4099993 | 0.72 | CA12 (1.00) | NOS3NOS2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6015851-A | MELT PROCESSABILITY | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2000-01-18 | — | — | US | disclosed |
| EP-0965612-A1 | Rubber compositions containig bis anil compounds | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 1999-12-22 | — | — | EP | disclosed |