Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRA1D | P25100 | 3/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.35 |
| ▸ | CA3 | P07451 | 1/20 | 0.34 |
| ▸ | CA6 | P23280 | 1/20 | 0.34 |
| ▸ | CA5A | P35218 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.34 |
| ▸ | DAO | P14920 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL98327 | 0.81 | ADRA1D (0.40) | ADRA1D | |
| SCHEMBL12749278 | 0.81 | MAOB (0.41) | — | |
| SCHEMBL3066192 | 0.81 | ALOX5AP (0.46) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL514459 | 0.80 | L3MBTL1 (0.47) | DAO | |
| SCHEMBL5541035 | 0.74 | MRGPRX4 (0.47) | PTGDR2 | |
| SCHEMBL1547698 | 0.74 | CA3 (0.38) | ADRA1DCES2CES1CA3CA6 | |
| SCHEMBL1539296 | 0.74 | L3MBTL1 (0.53) | — | |
| SCHEMBL2555360 | 0.73 | CTSS (0.53) | ADRA1DCES2CES1 | |
| SCHEMBL5534923 | 0.73 | SLC6A2 (0.40) | CES2CES1DAO | |
| SCHEMBL3070242 | 0.72 | KDM4E (0.54) | ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6048880-A | THERAPY FOR CYTOKINE SENSITIVE DISEASES | PFIZER PHARAMACEUTICALS INC. (JP) | 2000-04-11 | — | — | US | disclosed |