Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.41 |
| ▸ | NCOA3 | Q9Y6Q9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | NAMPT | P43490 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068354 | 0.92 | PSEN1 (0.47) | PAX8ALDH1A1TSHR | |
| SCHEMBL8053617 | 0.91 | RAB9A (0.44) | RAB9ANAMPT | |
| SCHEMBL8062528 | 0.91 | RAB9A (0.50) | RAB9APAX8 | |
| SCHEMBL8063759 | 0.90 | HTR1A (0.42) | RAB9A | |
| SCHEMBL8062526 | 0.87 | NPC1 (0.38) | RAB9AALDH1A1 | |
| SCHEMBL4542837 | 0.86 | RAB9A (0.53) | RAB9APAX8NCOA1NCOA3 | |
| SCHEMBL8061501 | 0.84 | HSD11B1 (0.49) | — | |
| SCHEMBL8060003 | 0.81 | RAB9A (0.41) | RAB9APAX8ALDH1A1TSHR | |
| SCHEMBL4535257 | 0.80 | RAB9A (0.53) | RAB9APAX8NCOA1NCOA3ALDH1A1 | |
| SCHEMBL8062873 | 0.79 | HCRTR1 (0.42) | ALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |