Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.38 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 2/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4541739 | 0.87 | EPHX2 (0.48) | HCRTR1ALDH1A1MEN1KMT2AEPHX1 | |
| SCHEMBL8062526 | 0.85 | NPC1 (0.38) | ALDH1A1KMT2AEPHX1EPHX2 | |
| SCHEMBL8053617 | 0.83 | RAB9A (0.44) | EPHX1EPHX2 | |
| SCHEMBL8068363 | 0.83 | HCRTR1 (0.41) | HCRTR1ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL8061501 | 0.81 | HSD11B1 (0.49) | — | |
| SCHEMBL8066489 | 0.79 | RAB9A (0.43) | HCRTR1 | |
| SCHEMBL8066636 | 0.79 | RAB9A (0.46) | ALDH1A1GAA | |
| SCHEMBL8068354 | 0.79 | PSEN1 (0.47) | ALDH1A1L3MBTL1EPHX2 | |
| SCHEMBL8063759 | 0.78 | HTR1A (0.42) | EPHX2 | |
| SCHEMBL8060003 | 0.77 | RAB9A (0.41) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009070497-A1 | SEH AND 11 β-HSD1 INHIBITORS AND THEIR USE | SMITHKLINE BEECHAM CORPORATION (US) | 2009-06-04 | — | — | WO | disclosed |