Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DAGLA | Q9Y4D2 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 3/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.31 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | FAAH | O00519 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2494950 | 0.80 | KDM4E (0.48) | DAGLAKDM4ERAB9AGLO1NPC1 | |
| SCHEMBL6819064 | 0.78 | MEN1 (0.46) | KDM4ERAB9ANPC1L3MBTL1POLB | |
| SCHEMBL28752612 | 0.74 | ATP4A (0.43) | KDM4ERAB9ANPC1MAPTSMN1; SMN2 | |
| SCHEMBL27624849 | 0.71 | TOP2A (0.44) | KDM4ERAB9ANPC1POLBMAPT | |
| SCHEMBL11133076 | 0.68 | RAB9A (0.38) | DAGLAKDM4ERAB9AGLO1NPC1 | |
| SCHEMBL12411252 | 0.67 | NPC1 (0.49) | RAB9ANPC1L3MBTL1MAPTNPSR1 | |
| SCHEMBL11206642 | 0.67 | NPC1 (0.49) | RAB9ANPC1L3MBTL1MAPTNPSR1 | |
| SCHEMBL9195617 | 0.66 | TDP1 (0.45) | KDM4ERAB9ANPC1L3MBTL1MAPT | |
| SCHEMBL476618 | 0.65 | KDM4E (0.49) | DAGLAKDM4ERAB9AGLO1NPC1 | |
| SCHEMBL8067648 | 0.65 | MEN1 (0.43) | RAB9ANPC1L3MBTL1MAPTNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6017665-A | CHARGE GENERATION LAYER COATED ONTO A SUBSTRATE FROM A COATING SOLUTION CONTAINING BINDER, CHARGE GENERATING MATERIAL, AND AN ORGANOSILANE COMPOUND; ADHESION, DURABILITY | MITSUBISHI CHEMICAL AMERICA (US) | 2000-01-25 | — | — | US | disclosed |