Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 7/20 | 0.39 |
| ▸ | HRH1 | P35367 | 7/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | PREP | P48147 | 1/20 | 0.36 |
| ▸ | CTSC | P53634 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2891232 | 0.85 | GPR119 (0.46) | HRH2HRH1 | |
| SCHEMBL2894483 | 0.85 | GPR119 (0.46) | HRH2HRH1 | |
| SCHEMBL2891228 | 0.85 | GPR119 (0.46) | HRH2HRH1 | |
| SCHEMBL2894479 | 0.85 | GPR119 (0.46) | HRH2HRH1 | |
| SCHEMBL8070465 | 0.84 | SCN9A (0.36) | HRH2HRH1SCN9ACTSCPTPN1 | |
| SCHEMBL8076407 | 0.77 | ITGB3 (0.53) | HRH2HRH1 | |
| SCHEMBL6161175 | 0.76 | CTSS (0.56) | SCN9AKMT2APREPPTPN1 | |
| SCHEMBL6160825 | 0.76 | CTSS (0.56) | SCN9AKMT2APREPPTPN1 | |
| SCHEMBL8066212 | 0.75 | PTPN1 (0.37) | HRH2HRH1PTPN1 | |
| SCHEMBL8076548 | 0.75 | HRH2 (0.38) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |