SCHEMBL8070465 — predicted protein targets

Predicted protein targets (top 10)

	gene	UniProt	supporting neighbours	confidence
▸	SCN9A	Q15858	8/20	0.36

▸	HRH2	P25021	4/20	0.36

▸	HRH1	P35367	4/20	0.36

▸	CTSC	P53634	1/20	0.36

▸	ACE	P12821	1/20	0.35

▸	PTPN1	P18031	1/20	0.35

▸	GPR119	Q8TDV5	1/20	0.34

▸	XIAP	P98170	1/20	0.34

▸	F2	P00734	1/20	0.34

▸	PRSS1	P07477	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL8068236	0.84	HRH2 (0.39)	SCN9AHRH2HRH1CTSCPTPN1
SCHEMBL8069233	0.79	HRH2 (0.35)	HRH2HRH1CTSCGPR119F2
SCHEMBL8058055	0.78	ELANE (0.36)	HRH2HRH1ACEGPR119F2
SCHEMBL2891309	0.76	GPR119 (0.45)	HRH2HRH1GPR119XIAPF2
SCHEMBL2891305	0.76	GPR119 (0.45)	HRH2HRH1GPR119XIAPF2
SCHEMBL2900663	0.76	GPR119 (0.45)	HRH2HRH1GPR119
SCHEMBL2900659	0.76	GPR119 (0.45)	HRH2HRH1GPR119
SCHEMBL8066212	0.75	PTPN1 (0.37)	HRH2HRH1PTPN1GPR119
SCHEMBL8057985	0.74	HRH2 (0.35)	HRH2HRH1PTPN1GPR119
SCHEMBL8080722	0.73	HRH2 (0.36)	HRH2HRH1ACE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2009034388-A1	COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS	PROSIDION LIMITED (GB)	2009-03-19	—	—	WO	disclosed