Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 2/20 | 0.37 |
| ▸ | CA3 | P07451 | 1/20 | 0.33 |
| ▸ | CA6 | P23280 | 1/20 | 0.33 |
| ▸ | CA5A | P35218 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.33 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.33 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.33 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.32 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.32 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.32 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 3/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | CA12 | O43570 | 1/20 | 0.31 |
| ▸ | CA7 | P43166 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL796657 | 0.81 | CCR2 (0.41) | CCR2EGLN1CA2CA1PTGS2 | |
| SCHEMBL17056247 | 0.78 | CA3 (0.33) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL13003581 | 0.76 | L3MBTL1 (0.41) | CCR2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL17158071 | 0.74 | PKM (0.38) | CCR2CA9CA2CA1PTGS2 | |
| SCHEMBL806713 | 0.74 | CA12 (0.39) | CCR2CA6CA5ACA9CA14 | |
| SCHEMBL24651345 | 0.73 | L3MBTL1 (0.42) | CCR2PIK3CDPIK3CAPIK3CBPIK3CG | |
| SCHEMBL1128576 | 0.72 | ENPP2 (0.45) | CCR2ENPP2PIK3CDPIK3CAPIK3CB | |
| SCHEMBL22396850 | 0.72 | ENPP2 (0.45) | CCR2ENPP2L3MBTL1 | |
| SCHEMBL5513421 | 0.72 | CA9 (0.53) | CA3CA6CA5ACA9CA14 | |
| SCHEMBL806761 | 0.71 | SMN1; SMN2 (0.47) | PTGS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037393-A1 | PIPERIDINYL-SUBSTITUTED LACTAMS AS GPR119 MODULATORS | ARRAY BIOPHARMA INC. (US) | 2012-03-22 | — | — | WO | disclosed |