Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR2 | P41597 | 3/20 | 0.44 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.41 |
| ▸ | SPHK1 | Q9NYA1 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 5/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068975 | 1.00 | CCR2 (0.44) | CCR2SPHK2SPHK1OPRM1OPRD1 | |
| SCHEMBL14626061 | 0.72 | RAB9A (0.51) | RAB9ASMN1; SMN2ACHE | |
| SCHEMBL11462791 | 0.72 | CCR2 (0.49) | CCR2SPHK2SPHK1 | |
| SCHEMBL5378500 | 0.71 | CASP3 (0.43) | RAB9ASMN1; SMN2ACHE | |
| SCHEMBL11459718 | 0.71 | CCR2 (0.49) | CCR2SPHK2SPHK1 | |
| SCHEMBL14591100 | 0.71 | RAB9A (0.47) | RAB9ASMN1; SMN2ACHE | |
| SCHEMBL7552049 | 0.71 | CXCR4 (0.56) | CCR2SPHK2SPHK1 | |
| SCHEMBL14454201 | 0.70 | CCR2 (0.48) | CCR2SPHK2SPHK1 | |
| SCHEMBL252661 | 0.70 | HRH3 (0.37) | SPHK2SPHK1 | |
| SCHEMBL11455659 | 0.70 | FAAH (0.52) | SPHK2SPHK1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000237595-A | ASYMMETRIC DI- OR TRIAMINE CATALYST CARRIED ON POLYMER | NISSAN CHEM IND LTD | 2000-09-05 | — | — | JP | disclosed |