Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLA | P06280 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 5/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | CYSLTR1 | Q9Y271 | 6/20 | 0.42 |
| ▸ | CYSLTR2 | Q9NS75 | 5/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 3/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.40 |
| ▸ | NR0B1 | P51843 | 1/20 | 0.38 |
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073563 | 1.00 | GLA (0.42) | GLARAB9ANPC1KDM4ELMNA | |
| Trifluoroacetic Acid SCHEMBL8067343 | 0.92 | CYSLTR1 (0.39) | GLARAB9ANPC1KDM4ELMNA | |
| SCHEMBL8069062 | 0.84 | IP6K1 (0.46) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL8069058 | 0.84 | IP6K1 (0.46) | RAB9ANPC1KDM4EMAPTMEN1 | |
| SCHEMBL8058054 | 0.83 | ALDH1A1 (0.41) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL8058059 | 0.83 | ALDH1A1 (0.41) | RAB9ANPC1KDM4ELMNAPKM | |
| SCHEMBL8073292 | 0.79 | IP6K1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8073308 | 0.79 | IP6K1 (0.41) | RAB9ANPC1MAPTSMN1; SMN2ALDH1A1 | |
| SCHEMBL8066788 | 0.78 | PADI4 (0.40) | RAB9ANPC1MAPTMEN1KMT2A | |
| SCHEMBL7825535 | 0.78 | KIF11 (0.43) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6093714-A | AN ANTIALLERGENS FOR TREATMENT AND PREVENTION OF BRONCHIAL ASTHMA, ECZEMA, HIVES, ALLERGIC GASTROINTESTINAL TROUBLES, ALLERGIC RHINITIS, ALLERGIC CONJUNCTIVITIS | MEIJI SEIKA KAISHA, LTD. (JP) | 2000-07-25 | — | — | US | disclosed |