Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 8/20 | 0.35 |
| ▸ | HRH1 | P35367 | 8/20 | 0.35 |
| ▸ | GPR119 | Q8TDV5 | 4/20 | 0.35 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | CTSC | P53634 | 1/20 | 0.32 |
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.32 |
| ▸ | CMA1 | P23946 | 1/20 | 0.32 |
| ▸ | ACACB | O00763 | 1/20 | 0.32 |
| ▸ | F2 | P00734 | 1/20 | 0.32 |
| ▸ | F10 | P00742 | 1/20 | 0.32 |
| ▸ | F11 | P03951 | 1/20 | 0.32 |
| ▸ | F7 | P08709 | 1/20 | 0.32 |
| ▸ | F3 | P13726 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073645 | 0.92 | HRH2 (0.36) | HRH2HRH1ELANE | |
| SCHEMBL8080722 | 0.92 | HRH2 (0.36) | HRH2HRH1ELANE | |
| SCHEMBL8058055 | 0.91 | ELANE (0.36) | HRH2HRH1GPR119ELANECMA1 | |
| SCHEMBL8066212 | 0.85 | PTPN1 (0.37) | HRH2HRH1GPR119 | |
| SCHEMBL8057985 | 0.85 | HRH2 (0.35) | HRH2HRH1GPR119ACACB | |
| SCHEMBL8066147 | 0.83 | ELANE (0.35) | HRH2HRH1ELANECMA1F2 | |
| SCHEMBL8070465 | 0.79 | SCN9A (0.36) | HRH2HRH1GPR119CTSCF2 | |
| SCHEMBL8076548 | 0.77 | HRH2 (0.38) | HRH2HRH1GPR119 | |
| SCHEMBL2898078 | 0.77 | GPR119 (0.42) | HRH2HRH1GPR119ELANEHRH3 | |
| SCHEMBL2898073 | 0.77 | GPR119 (0.42) | HRH2HRH1GPR119ELANEHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |