Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 12/20 | 0.36 |
| ▸ | HRH1 | P35367 | 12/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | ELANE | P08246 | 1/20 | 0.32 |
| ▸ | ACE | P12821 | 1/20 | 0.32 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073645 | 1.00 | HRH2 (0.36) | HRH2HRH1KDM4ENPSR1ELANE | |
| SCHEMBL8069233 | 0.92 | HRH2 (0.35) | HRH2HRH1ELANE | |
| SCHEMBL8066147 | 0.91 | ELANE (0.35) | HRH2HRH1NPSR1ELANEACE | |
| SCHEMBL8073128 | 0.85 | HRH2 (0.36) | HRH2HRH1KDM4E | |
| SCHEMBL8073649 | 0.85 | ITGB3 (0.37) | HRH2HRH1 | |
| SCHEMBL8058055 | 0.83 | ELANE (0.36) | HRH2HRH1NPSR1ELANEACE | |
| SCHEMBL8057985 | 0.77 | HRH2 (0.35) | HRH2HRH1 | |
| SCHEMBL8066212 | 0.76 | PTPN1 (0.37) | HRH2HRH1 | |
| SCHEMBL13027124 | 0.76 | GPR119 (0.37) | HRH2HRH1ELANE | |
| SCHEMBL2897670 | 0.76 | GPR119 (0.37) | HRH2HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |