Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 17/20 | 0.53 |
| ▸ | PTGS1 | P23219 | 6/20 | 0.46 |
| ▸ | MAP4K1 | Q92918 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8068397 | 0.88 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL8058037 | 0.84 | PTGS2 (0.57) | PTGS2PTGS1 | |
| SCHEMBL8199737 | 0.83 | PTGS2 (0.40) | PTGS2PTGS1ALDH1A1APOBEC3G | |
| SCHEMBL8637748 | 0.82 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8200031 | 0.82 | PTGS2 (0.39) | PTGS2PTGS1ALDH1A1APOBEC3G | |
| SCHEMBL8067283 | 0.82 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8640822 | 0.77 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8073634 | 0.76 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8074136 | 0.75 | EPAS1 (0.42) | PTGS2PTGS1 | |
| SCHEMBL8197292 | 0.74 | PTGS2 (0.40) | PTGS2PTGS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | claimed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | claimed |