Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 6/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 4/20 | 0.39 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | BRD4 | O60885 | 1/20 | 0.33 |
| ▸ | BRD2 | P25440 | 1/20 | 0.33 |
| ▸ | BRD3 | Q15059 | 1/20 | 0.33 |
| ▸ | TASP1 | Q9H6P5 | 1/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200031 | 0.94 | PTGS2 (0.39) | PTGS2PTGS1PTGDR2CA2ALDH1A1 | |
| SCHEMBL8197292 | 0.91 | PTGS2 (0.40) | PTGS2PTGS1PTGDR2CA2ALDH1A1 | |
| SCHEMBL8194817 | 0.87 | PTGS2 (0.40) | PTGS2PTGS1PTGDR2CA2ALDH1A1 | |
| SCHEMBL8195877 | 0.87 | PTGS2 (0.41) | PTGS2PTGS1PTGDR2CA2ALDH1A1 | |
| SCHEMBL8196861 | 0.86 | PTGS2 (0.43) | PTGS2PTGS1ALDH1A1LMNA | |
| SCHEMBL8201297 | 0.86 | L3MBTL1 (0.37) | PTGS2CA2ALDH1A1LMNAMAPT | |
| SCHEMBL8196899 | 0.85 | PTGS2 (0.39) | PTGS2PTGS1PTGDR2CA2ALDH1A1 | |
| SCHEMBL8069284 | 0.83 | PTGS2 (0.53) | PTGS2PTGS1ALDH1A1APOBEC3G | |
| SCHEMBL8195776 | 0.83 | CA2 (0.41) | PTGS2PTGS1CA2LMNAMAPT | |
| SCHEMBL8196142 | 0.83 | PTGS2 (0.37) | PTGS2PTGS1PTGDR2CA2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000018741-A2 | PYRAZOLE COMPOUNDS AS COX-2 INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-04-06 | — | — | WO | disclosed |