Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPAS1 | Q99814 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 16/20 | 0.41 |
| ▸ | FYN | P06241 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8058037 | 0.85 | PTGS2 (0.57) | PTGS2FYNPTGS1 | |
| SCHEMBL8640822 | 0.79 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8637748 | 0.75 | PTGS2 (0.56) | PTGS2PTGS1 | |
| SCHEMBL8069284 | 0.75 | PTGS2 (0.53) | PTGS2PTGS1 | |
| SCHEMBL8068397 | 0.73 | PTGS2 (0.53) | PTGS2 | |
| SCHEMBL8196846 | 0.73 | AR (0.39) | — | |
| SCHEMBL8067283 | 0.72 | PTGS2 (0.49) | PTGS2PTGS1 | |
| SCHEMBL8196861 | 0.72 | PTGS2 (0.43) | PTGS2PTGS1 | |
| SCHEMBL8196687 | 0.72 | PTGS2 (0.41) | PTGS2PTGS1 | |
| SCHEMBL8200042 | 0.71 | AR (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1017678-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-07-12 | — | — | EP | disclosed |
| WO-1999015505-A1 | 1,5-DIPHENYLPYRAZOLE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-04-01 | — | — | WO | disclosed |