SCHEMBL8070036

SCHEMBL8070036

Cc1cc(O)c(C)c(C)c1C(c1cccc(O)c1O)c1c(C)cc(O)c(C)c1C

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TRPA1 O75762 2/20 0.42
ATM Q13315 1/20 0.38
GUSB P08236 1/20 0.37
BCHE P06276 1/20 0.37
TYR P14679 1/20 0.37
ACHE P22303 1/20 0.37
LMNA P02545 6/20 0.35
HPGD P15428 5/20 0.35
ALDH1A1 P00352 5/20 0.35
ALOX15 P16050 4/20 0.35
HSD17B10 Q99714 4/20 0.35
CA1 P00915 2/20 0.35
CA2 P00918 2/20 0.35
ADAMTS4 O75173 1/20 0.35
EGFR P00533 1/20 0.35
FYN P06241 1/20 0.35
MMP2 P08253 1/20 0.35
MMP9 P14780 1/20 0.35
MMP8 P22894 1/20 0.35
CA6 P23280 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863828 0.86 GABRA1 (0.44) TRPA1ATMACHELMNAHPGD
SCHEMBL30375425 0.86 GABRA1 (0.44) TRPA1ATMACHELMNAHPGD
SCHEMBL4055507 0.78 CA1 (0.43) BCHETYRACHELMNAHPGD
SCHEMBL2860977 0.74 TRPA1 (0.47) TRPA1ATMGUSBBCHETYR
SCHEMBL835192 0.74 SLC6A2 (0.37) TRPA1ATMTYRLMNAHPGD
SCHEMBL30374777 0.71 GABRA1 (0.42) TRPA1ATMLMNAHPGDALDH1A1
SCHEMBL5385164 0.71 GABRA1 (0.42) TRPA1ATMLMNAHPGDALDH1A1
SCHEMBL4058120 0.70 ESR1 (0.39) TRPA1ACHELMNAHPGDALDH1A1
SCHEMBL4062276 0.70 KMT2A (0.40) TRPA1ACHELMNAHPGDALDH1A1
SCHEMBL11430528 0.69 TRPA1 (0.54) TRPA1ATMACHELMNAHPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1035438-A2 Phenolic resins and photoresist compositions comprising same Shipley Company LLC (US) 2000-09-13 EP disclosed