SCHEMBL30375425

SCHEMBL30375425

Cc1cc(O)c(C)c(C)c1C(c1ccccc1O)c1c(C)cc(O)c(C)c1C

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.44
GABRB2 P47870 1/20 0.44
MAPT P10636 5/20 0.42
KMT2A Q03164 4/20 0.42
LMNA P02545 4/20 0.42
MEN1 O00255 2/20 0.42
TSHR P16473 1/20 0.40
TRPA1 O75762 2/20 0.36
ATM Q13315 1/20 0.36
HTT P42858 2/20 0.36
CYP3A4 P08684 3/20 0.34
ALOX15 P16050 3/20 0.34
HIF1A Q16665 3/20 0.34
CYP1A2 P05177 2/20 0.34
CYP2D6 P10635 2/20 0.34
CYP2C9 P11712 2/20 0.34
PKM P14618 2/20 0.34
CYP2C19 P33261 2/20 0.34
THRB P10828 2/20 0.34
POLB P06746 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2863828 1.00 GABRA1 (0.44) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL8070036 0.86 TRPA1 (0.42) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL4055507 0.83 CA1 (0.43) MAPTKMT2ALMNAMEN1TSHR
SCHEMBL7187040 0.81 GABRA1 (0.47) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL4027621 0.81 GABRA1 (0.47) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL5385164 0.81 GABRA1 (0.42) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL30374777 0.81 GABRA1 (0.42) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL835192 0.80 SLC6A2 (0.37) MAPTKMT2ALMNAMEN1TRPA1
SCHEMBL2313593 0.79 GABRA1 (0.44) GABRA1GABRB2MAPTKMT2ALMNA
SCHEMBL30149174 0.79 GABRA1 (0.44) GABRA1GABRB2MAPTKMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113646052-B Reversible thermochromic composition, reversible thermochromic microcapsule pigment, and writing instrument 百乐墨水株式会社 2024-05-17 CN disclosed
CN-113785023-B Water-based ink composition for reversible thermochromic writing instrument, refill for refill and water-based ballpoint pen incorporating same 株式会社百乐 2023-05-12 CN disclosed