Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR4 | P51679 | 11/20 | 0.56 |
| ▸ | EHMT2 | Q96KQ7 | 8/20 | 0.56 |
| ▸ | WHR1 | P49842 | 1/20 | 0.53 |
| ▸ | EHMT1 | Q9H9B1 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8070274 | 0.89 | CCR4 (0.52) | CCR4EHMT2WHR1EHMT1 | |
| SCHEMBL8070244 | 0.85 | EHMT2 (0.52) | EHMT2WHR1EHMT1 | |
| SCHEMBL8071911 | 0.84 | ADRA1A (0.62) | — | |
| SCHEMBL8061122 | 0.79 | HDAC1 (0.47) | EHMT2EHMT1 | |
| SCHEMBL8071856 | 0.78 | MGLL (0.47) | EHMT2EHMT1 | |
| SCHEMBL8077026 | 0.77 | ADRA1A (0.60) | — | |
| SCHEMBL8061075 | 0.74 | EHMT2 (0.48) | EHMT2WHR1EHMT1 | |
| SCHEMBL8076826 | 0.74 | ADRA1A (0.56) | — | |
| SCHEMBL8071748 | 0.73 | ADRA1A (0.60) | — | |
| SCHEMBL15280598 | 0.73 | CCR4 (0.67) | CCR4EHMT2WHR1EHMT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6156758-A | Antibacterial quinazoline compounds | ISIS PHARMACEUTICALS, INC. (US) | 2000-12-05 | — | — | US | disclosed |