Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.40 |
| ▸ | FEN1 | P39748 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.38 |
| ▸ | ERN1 | O75460 | 7/20 | 0.38 |
| ▸ | AR | P10275 | 2/20 | 0.38 |
| ▸ | TNKS | O95271 | 1/20 | 0.37 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | DRD1 | P21728 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | PTPRC | P08575 | 1/20 | 0.34 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2476180 | 0.80 | TNKS (0.46) | ALOX5APFEN1XDHERN1TNKS | |
| SCHEMBL3161240 | 0.76 | XDH (0.41) | ALOX5APFEN1XDHERN1TNKS | |
| SCHEMBL5094485 | 0.76 | KIF11 (0.42) | ALOX5APFEN1XDHERN1AR | |
| SCHEMBL2477166 | 0.76 | PTGER1 (0.47) | ALOX5APFEN1XDHERN1TNKS | |
| SCHEMBL2474403 | 0.76 | PDE3B (0.45) | ALOX5APFEN1XDHERN1TNKS | |
| SCHEMBL5723222 | 0.74 | ALDH1A1 (0.48) | XDHMEN1LMNATHRBBLM | |
| SCHEMBL23480395 | 0.73 | ALOX5AP (0.42) | ALOX5APFEN1ERN1TNKSTNKS2 | |
| SCHEMBL1576019 | 0.73 | ALDH1A1 (0.47) | MEN1KMT2ATDP1DRD1ALDH1A1 | |
| SCHEMBL6536177 | 0.73 | LMNA (0.46) | XDHMEN1LMNATHRBBLM | |
| SCHEMBL3941247 | 0.73 | XDH (0.41) | XDHERN1MEN1LMNATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020379-A | Position 7 substituted indenyl-3-acetic acid derivatives and amides thereof for the treatment of neoplasia | CELL PATHWAYS, INC. (US) | 2000-02-01 | — | — | US | disclosed |