Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA2 | P00918 | 10/20 | 0.43 |
| ▸ | CA1 | P00915 | 9/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 6/20 | 0.38 |
| ▸ | CA12 | O43570 | 5/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | F10 | P00742 | 2/20 | 0.37 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.37 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.37 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.37 |
| ▸ | NQO2 | P16083 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8071784 | 0.99 | CA2 (0.42) | CA2CA1TSHRNAMPTCA9 | |
| SCHEMBL8070598 | 0.85 | CA2 (0.45) | CA2CA1TSHRNAMPTCA9 | |
| SCHEMBL8059472 | 0.85 | TSHR (0.39) | TSHRF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8070516 | 0.85 | SLC9A1 (0.44) | CA2CA1 | |
| Hydrochloric Acid SCHEMBL8375664 | 0.84 | TSHR (0.38) | TSHRMEN1KMT2AF10PRSS1 | |
| SCHEMBL8438279 | 0.83 | ITGB3 (0.49) | CA2CA1PPARA | |
| SCHEMBL8068683 | 0.82 | SMN1; SMN2 (0.41) | TSHRF10 | |
| SCHEMBL8059397 | 0.82 | THRA (0.42) | TSHRF10PRSS1PRSS2PRSS3 | |
| SCHEMBL8059495 | 0.81 | THRA (0.41) | TSHRF10PRSS1PRSS2PRSS3 | |
| Hydrochloric Acid SCHEMBL8059609 | 0.81 | SMN1; SMN2 (0.40) | TSHRF10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057322-A | USEFUL IN TREATMENT OF CARDIOVASCULAR DISEASES | HOECHST AKTIENGESELLSCHAFT (DE) | 2000-05-02 | — | — | US | disclosed |