Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SRC | P12931 | 2/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | FYN | P06241 | 2/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.46 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.46 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.46 |
| ▸ | PRKCI | P41743 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
| ▸ | GPR68 | Q15743 | 1/20 | 0.45 |
| ▸ | BACE1 | P56817 | 1/20 | 0.44 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.43 |
| ▸ | ATR | Q13535 | 1/20 | 0.43 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.43 |
| ▸ | CDK8 | P49336 | 1/20 | 0.42 |
| ▸ | LIMK1 | P53667 | 1/20 | 0.42 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10277962 | 0.83 | HSD17B1 (0.51) | MEN1NPC1RAB9AKMT2ASRC | |
| SCHEMBL807074 | 0.76 | FGFR1 (0.57) | MEN1NPC1RAB9AKMT2ASRC | |
| Hydrochloric Acid SCHEMBL789680 | 0.74 | FGFR1 (0.55) | MEN1NPC1RAB9AKMT2ASRC | |
| SCHEMBL8574353 | 0.73 | KMT2A (0.74) | MEN1NPC1RAB9AKMT2ASRC | |
| SCHEMBL790060 | 0.73 | FGFR1 (0.54) | MEN1NPC1RAB9AKMT2ASRC | |
| SCHEMBL30108284 | 0.73 | PRKCI (0.70) | FGFR1FYNPRKCIHTR1AGPR68 | |
| SCHEMBL249824 | 0.73 | PRKCI (0.70) | FGFR1FYNPRKCIHTR1AGPR68 | |
| SCHEMBL789883 | 0.72 | MAP4K4 (0.54) | MEN1NPC1RAB9AKMT2ASRC | |
| SCHEMBL23750160 | 0.71 | PRKCI (0.63) | MEN1NPC1RAB9AKMT2AFGFR1 | |
| SCHEMBL4191589 | 0.71 | PRKCI (0.72) | FGFR1FYNPRKCIACMSDCDK8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |