Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 2/20 | 0.62 |
| ▸ | CA1 | P00915 | 2/20 | 0.62 |
| ▸ | CA2 | P00918 | 2/20 | 0.62 |
| ▸ | CA7 | P43166 | 2/20 | 0.62 |
| ▸ | CA9 | Q16790 | 2/20 | 0.62 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.62 |
| ▸ | HSD17B2 | P37059 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 7/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.53 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.53 |
| ▸ | RNASEL | Q05823 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13529206 | 0.96 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL27734000 | 0.94 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL2312401 | 0.94 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11340705 | 0.94 | CA12 (0.59) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13693079 | 0.93 | ESR1 (0.65) | ESR1CYP1A2CYP2D6TSHRCYP2C19 | |
| SCHEMBL13529205 | 0.93 | CA12 (0.64) | CA12CA1CA2CA7CA9 | |
| SCHEMBL13529210 | 0.88 | CA12 (0.62) | CA12CA1CA2CA7CA9 | |
| SCHEMBL8358255 | 0.88 | CYP1A2 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1990526 | 0.88 | CA12 (0.70) | CA12CA1CA2CA7CA9 | |
| SCHEMBL643931 | 0.87 | CA12 (0.60) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2890686-B1 | METHOD FOR PRODUCING OXAZOLE COMPOUND | OTSUKA PHARMA CO LTD (JP) | 2017-01-04 | — | — | EP | disclosed |
| US-9181205-B2 | Method for producing oxazole compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-11-10 | — | — | US | disclosed |
| US-20150239855-A1 | Method for Producing Oxazole Compound | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2015-08-27 | — | — | US | disclosed |
| WO-2014034958-A1 | METHOD FOR PRODUCING OXAZOLE COMPOUND | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2014-03-06 | — | — | WO | disclosed |
| US-20100056497-A1 | AMIDE DERIVATIVE | DAINIPPON SUMITOMO PHARMA CO., LTD (JP) | 2010-03-04 | — | — | US | disclosed |
| US-20100056575-A1 | Anesthetic Compounds | SIGNATURE THERAPEUTICS, INC. | 2010-03-04 | — | — | US | disclosed |
| EP-2119702-A1 | AMIDE DERIVATIVE | Dainippon Sumitomo Pharma Co., Ltd. (JP) | 2009-11-18 | — | — | EP | disclosed |
| WO-2009036055-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. (US) | 2009-03-19 | — | — | WO | disclosed |
| US-20090076044-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | CURIS, INC. | 2009-03-19 | — | — | US | disclosed |
| WO-2008011539-A2 | ANESTHETIC COMPOUNDS | PHARMACOFORE, INC. (US) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150239855-A1 | Method for Producing Oxazole Compound | OXA1L, CYB5R3, CBR3 | CA12 596/4885CA1 949/4885CA2 318/4885 |
| US-20090076044-A1 | VEGFR INHIBITORS CONTAINING A ZINC BINDING MOIETY | KDR, HDAC1, FLT4 | CA12 2762/4885CA1 3453/4885CA2 2413/4885 |
| US-20100056575-A1 | Anesthetic Compounds | OPRL1, OPRM1, CYP3A5 | CA12 493/4885CA1 22/4885CA2 38/4885 |
| US-20100056497-A1 | AMIDE DERIVATIVE | REN, AGTR1, AGTR2 | CA12 977/4885CA1 804/4885CA2 168/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.