Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 5/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | GFER | P55789 | 1/20 | 0.36 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 5/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | CYTH2 | Q99418 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13268020 | 0.88 | PIK3CD (0.51) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13180233 | 0.80 | PIK3CB (0.43) | GAAALDH1A1PIK3CGMEN1KMT2A | |
| SCHEMBL12724541 | 0.78 | PIK3CD (0.48) | PIK3CDPIK3CA | |
| SCHEMBL12724454 | 0.77 | LMNA (0.42) | SLC40A1ALDH1A1PIK3CGPIK3CDMEN1 | |
| SCHEMBL8414791 | 0.74 | FBP1 (0.42) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL807318 | 0.73 | SLC40A1 (0.38) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13034959 | 0.73 | PIK3C3 (0.35) | PIK3CA | |
| SCHEMBL9955288 | 0.73 | PIK3CG (0.52) | SLC40A1ALDH1A1PIK3CGPIK3CDPIK3CA | |
| SCHEMBL3115744 | 0.72 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL29555684 | 0.72 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |