Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC40A1 | Q9NP59 | 8/20 | 0.38 |
| ▸ | PIK3CG | P48736 | 8/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 4/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 2/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.34 |
| ▸ | KDR | P35968 | 1/20 | 0.34 |
| ▸ | PI4KA | P42356 | 1/20 | 0.34 |
| ▸ | PIK3C3 | Q8NEB9 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
| ▸ | G6PD | P11413 | 1/20 | 0.33 |
| ▸ | NFKBIA | P25963 | 1/20 | 0.33 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.33 |
| ▸ | METAP2 | P50579 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.33 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL791191 | 0.84 | PDGFRB (0.44) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL13268020 | 0.73 | PIK3CD (0.51) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL807174 | 0.73 | SLC40A1 (0.36) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL790432 | 0.73 | PIK3CA (0.45) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL9955288 | 0.71 | PIK3CG (0.52) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL3115744 | 0.70 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL29555684 | 0.70 | PIK3CD (0.57) | PIK3CGPIK3CDPIK3CAPIK3CBPI4KA | |
| SCHEMBL790162 | 0.69 | ALDH1A1 (0.51) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL790824 | 0.68 | ALPL (0.56) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB | |
| SCHEMBL29556839 | 0.68 | ALPL (0.56) | SLC40A1PIK3CGPIK3CDPIK3CAPIK3CB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012037108-A1 | AMINOQUINOLINE DERIVATIVES AS ANTIVIRAL AGENTS | GLAXOSMITHKLINE LLC (US) | 2012-03-22 | — | — | WO | disclosed |