Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 1/20 | 0.32 |
| ▸ | FEN1 | P39748 | 1/20 | 0.32 |
| ▸ | ESR1 | P03372 | 2/20 | 0.32 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.32 |
| ▸ | TNKS | O95271 | 1/20 | 0.31 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.31 |
| ▸ | PTPRC | P08575 | 1/20 | 0.30 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072390 | 0.81 | AKR1C3 (0.34) | — | |
| SCHEMBL8074245 | 0.79 | TAAR1 (0.35) | — | |
| SCHEMBL15471654 | 0.79 | ALOX5AP (0.43) | ALOX5APFEN1ESR1ESR2TNKS | |
| SCHEMBL8072992 | 0.77 | ESR1 (0.34) | ESR1ESR2 | |
| SCHEMBL29019414 | 0.76 | AKR1C3 (0.43) | TNKSTNKS2 | |
| SCHEMBL1045097 | 0.75 | AKR1C3 (0.44) | — | |
| SCHEMBL8079296 | 0.74 | HSD17B1 (0.41) | ESR1ESR2 | |
| SCHEMBL63751 | 0.74 | — | — | |
| SCHEMBL8077709 | 0.73 | RARB (0.39) | — | |
| SCHEMBL29019397 | 0.73 | PTGS2 (0.40) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |