Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 3/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.34 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.31 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.31 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.31 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.31 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.31 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.31 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.31 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | MAP2K4 | P45985 | 1/20 | 0.30 |
| ▸ | MAPKAPK2 | P49137 | 1/20 | 0.30 |
| ▸ | MAPKAPK3 | Q16644 | 1/20 | 0.30 |
| ▸ | MAPK6 | Q16659 | 1/20 | 0.30 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8072415 | 0.77 | ALOX5AP (0.32) | ESR1ESR2 | |
| SCHEMBL26036293 | 0.76 | ESR1 (0.44) | ESR1ESR2HSD17B1 | |
| SCHEMBL8064206 | 0.76 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL8074688 | 0.75 | ESR1 (0.31) | ESR1ESR2 | |
| SCHEMBL10916725 | 0.75 | HSD17B1 (0.45) | ESR1ESR2GRIN2DGRIN3BGRIN1 | |
| SCHEMBL28123521 | 0.74 | NOTUM (0.42) | ESR1ESR2HSD17B1 | |
| SCHEMBL8072989 | 0.74 | ESR1 (0.32) | ESR1ESR2 | |
| SCHEMBL8074556 | 0.74 | HTR2A (0.32) | — | |
| SCHEMBL13849401 | 0.73 | RXRA (0.35) | ESR1ESR2HSD17B1 | |
| SCHEMBL8074834 | 0.72 | ESR1 (0.38) | ESR1ESR2HSD17B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6166072-A | Amino acid derivatives | ALLELIX NEUROSCIENCE, INC. (CA) | 2000-12-26 | — | — | US | disclosed |