Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 6/20 | 0.36 |
| ▸ | HRH1 | P35367 | 6/20 | 0.36 |
| ▸ | ITGB3 | P05106 | 7/20 | 0.34 |
| ▸ | ITGA2B | P08514 | 7/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.33 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.33 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.33 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 1/20 | 0.33 |
| ▸ | AAK1 | Q2M2I8 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | GLA | P06280 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | ITGAV | P06756 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073649 | 0.93 | ITGB3 (0.37) | HRH2HRH1ITGB3ITGA2BITGAV | |
| SCHEMBL8057985 | 0.91 | HRH2 (0.35) | HRH2HRH1ITGB3ITGA2BSLC6A2 | |
| SCHEMBL8080722 | 0.85 | HRH2 (0.36) | HRH2HRH1KDM4E | |
| SCHEMBL8073645 | 0.85 | HRH2 (0.36) | HRH2HRH1KDM4E | |
| SCHEMBL8066147 | 0.84 | ELANE (0.35) | HRH2HRH1 | |
| SCHEMBL8066212 | 0.83 | PTPN1 (0.37) | HRH2HRH1ITGB3ITGA2BAAK1 | |
| SCHEMBL8076479 | 0.80 | ITGB3 (0.49) | HRH2HRH1ITGB3ITGA2BSLC6A4 | |
| SCHEMBL8072985 | 0.80 | ITGB3 (0.49) | HRH2HRH1ITGB3ITGA2BSLC6A4 | |
| SCHEMBL2890939 | 0.80 | GPR119 (0.40) | HRH2HRH1ACACB | |
| SCHEMBL2890936 | 0.80 | GPR119 (0.40) | HRH2HRH1ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009034388-A1 | COMPOUNDS FOR THE TREATMENT OF METABOLIC DISORDERS | PROSIDION LIMITED (GB) | 2009-03-19 | — | — | WO | disclosed |