Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | PTGES | O14684 | 6/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | MAOA | P21397 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7831864 | 0.88 | KDM4E (0.40) | KDM4EPTGESCYP2C9SMN1; SMN2HPGD | |
| SCHEMBL7826505 | 0.86 | PTGES (0.47) | PTGESCYP2C9MAOAHPGDTSHR | |
| SCHEMBL7815301 | 0.83 | KDM4E (0.42) | KDM4EMAOAMAPTNPC1RAB9A | |
| SCHEMBL7825628 | 0.83 | PTGES (0.46) | KDM4EPTGESCYP2C9MAOANPC1 | |
| SCHEMBL8068924 | 0.83 | PARP1 (0.38) | LMNATSHRALDH1A1HSD17B10PARP1 | |
| SCHEMBL7826259 | 0.82 | PTGES (0.51) | KDM4EPTGESCYP2C9MAPTNPC1 | |
| SCHEMBL8069100 | 0.80 | NPY5R (0.35) | LMNAGRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL7826265 | 0.80 | CSNK2A1 (0.41) | KDM4EMAOATP53PARP1DYRK1A | |
| SCHEMBL7828601 | 0.79 | PARP1 (0.37) | KDM4EPTGESCYP2C9LMNAHPGD | |
| SCHEMBL7817404 | 0.79 | LMNA (0.42) | KDM4EPTGESCYP2C9LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0686636-B1 | TRICYCLIC BENZAZEPINE AND BENZOTHIAZEPINE DERIVATIVES | MEIJI SEIKA CO (JP) | 2001-04-04 | — | — | EP | disclosed |