SCHEMBL8073706

SCHEMBL8073706

CC=C(C)C(=O)Oc1ccc(O)cc1C=Cc1ccccc1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PELI1 Q96FA3 3/20 0.43
BACE1 P56817 1/20 0.41
TUBB1 Q9H4B7 1/20 0.40
CAPN1 P07384 1/20 0.39
KDM4E B2RXH2 2/20 0.39
MEN1 O00255 2/20 0.39
ALDH1A1 P00352 2/20 0.39
CYP3A4 P08684 2/20 0.39
MAPT P10636 2/20 0.39
HPGD P15428 2/20 0.39
KMT2A Q03164 2/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
HSD17B10 Q99714 2/20 0.39
THRB P10828 1/20 0.39
ALOX15 P16050 1/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
GUSB P08236 1/20 0.39
PTPN1 P18031 1/20 0.39
USP2 O75604 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30876325 0.77 NFE2L2 (0.64) BACE1TUBB1CAPN1KDM4EMEN1
SCHEMBL7044144 0.74 HSD17B1 (0.38) BACE1CAPN1MEN1ALDH1A1CYP3A4
SCHEMBL28461032 0.73 TRPA1 (0.50) PELI1BACE1TUBB1CAPN1KDM4E
SCHEMBL29733304 0.72 NFE2L2 (0.56) KDM4EMEN1ALDH1A1CYP3A4MAPT
SCHEMBL16504636 0.71 KDM4E (0.42) KDM4EALDH1A1MAPTHPGDHSD17B10
SCHEMBL28967686 0.71 TUBB1 (0.53) BACE1TUBB1MEN1ALDH1A1MAPT
SCHEMBL238871 0.70 GLA (0.48) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL28048047 0.70 GLA (0.48) MEN1ALDH1A1MAPTKMT2ASMN1; SMN2
SCHEMBL4982103 0.69 NFE2L2 (0.61) TUBB1KDM4EMEN1ALDH1A1MAPT
SCHEMBL4982109 0.69 NFE2L2 (0.61) TUBB1KDM4EMEN1ALDH1A1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0582538-B1 Propylene carbonate recovery process IBM (US) 2000-10-11 EP disclosed
US-6127097-A EXPOSING PHOTORESIST FILM ON SUBSTRATE TO RADIATION TO CROSSLINK, DEVELOPING IN BENZYL ALCOHOL, FORMING COPPER CIRCUIT PATTERN, STRIPPING PHOTORESIST IN SOLUTION OF BENZYL ALCOHOL AND ADDITIONAL SOLVENT INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 2000-10-03 US disclosed
EP-0584030-B1 Process for the abatement of propylene carbonate emissions IBM (US) 1997-03-19 EP disclosed
EP-0584030-A1 Process for the abatement of propylene carbonate emissions INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-02-23 EP disclosed
EP-0582538-A2 Propylene carbonate recovery process INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-02-09 EP disclosed
EP-0582539-A1 Chemical pre-treatment and biological destruction of propylene carbonate waste effluent streams to reduce the biological oxygen demand thereof INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1994-02-09 EP disclosed
US-5281723-A Propylene carbonate recovery process INTERNATIONAL BUSINESS MACHINES (US) 1994-01-25 US disclosed
US-5268260-A Free radical initiated addition polymerizable acrylate monomer INTERNATIONAL BUSINESS MACHINES CORPORATION (US) 1993-12-07 US disclosed