Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.57 |
| ▸ | CA1 | P00915 | 1/20 | 0.57 |
| ▸ | CA2 | P00918 | 1/20 | 0.57 |
| ▸ | CA7 | P43166 | 1/20 | 0.57 |
| ▸ | CA9 | Q16790 | 1/20 | 0.57 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HSP90B1 | P14625 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL70573 | 0.82 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6265168 | 0.81 | ALOX5 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL31643781 | 0.81 | ALOX5 (0.63) | CA12CA1CA2CA7CA9 | |
| SCHEMBL11786743 | 0.80 | CA12 (0.58) | CA12CA1CA2CA7CA9 | |
| SCHEMBL161350 | 0.78 | CA12 (0.68) | CA12CA1CA2CA7CA9 | |
| SCHEMBL6501360 | 0.77 | MEN1 (0.54) | CA12CA1CA2CA7CA9 | |
| SCHEMBL30881996 | 0.77 | CA12 (0.55) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1791233 | 0.76 | KDM4E (0.66) | CA12CA1CA2CA7CA9 | |
| SCHEMBL1638703 | 0.76 | CA12 (0.60) | CA12CA1CA2CA7CA9 | |
| SCHEMBL3422904 | 0.76 | THRB (0.57) | CA12CA1CA2CA7CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6149841-A | COMPOUNDS SUCH AS 3,3-BIS(4-METHOXYPHENYL)-13-OXO-3,13-DIHYDROBENZO(B)PYRANO -(4',3':6,7)NAPHTHO(2,1-B)PYRAN; ACCEPTABLE FADE RATE WITHOUT THE ADDITION OF ACIDS OR BASES AND AN ACCEPTABLE COLORATION RATE AT ROOM TEMPERATURE | PPG INDUSTRIES OHIO, INC. (US) | 2000-11-21 | — | — | US | disclosed |