Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 7/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 11/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 4/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073995 | 0.84 | GPR174 (0.54) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8103160 | 0.80 | MAPT (0.62) | GPR174ALDH1A1MAPTSMN1; SMN2LMNA | |
| SCHEMBL8070760 | 0.79 | MAPT (0.50) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8074360 | 0.76 | GPR174 (0.45) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL6166846 | 0.71 | MAPT (0.59) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL1425030 | 0.71 | MAPT (0.55) | ALDH1A1MAPTSMN1; SMN2LMNAGAA | |
| SCHEMBL9302533 | 0.70 | GPR174 (0.67) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL14217252 | 0.70 | ALDH1A1 (0.70) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL9904163 | 0.70 | ALDH1A1 (0.53) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 | |
| SCHEMBL8068840 | 0.69 | GPR174 (0.43) | GPR174ALDH1A1MAPTMAPK1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |
| EP-0983263-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-03-08 | — | — | EP | disclosed |
| WO-1998054172-A1 | NOVEL BENZIMIDAZOLE DERIVATIVES AS ANTIULCER AGENTS, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S RESEARCH FOUNDATION (IN) | 1998-12-03 | — | — | WO | disclosed |