Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR174 | Q9BXC1 | 6/20 | 0.43 |
| ▸ | MAPT | P10636 | 8/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BRPF1 | P55201 | 2/20 | 0.37 |
| ▸ | BRD4 | O60885 | 1/20 | 0.37 |
| ▸ | BRD1 | O95696 | 1/20 | 0.37 |
| ▸ | BRPF3 | Q9ULD4 | 1/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8073995 | 0.75 | GPR174 (0.54) | GPR174MAPTLMNAGAAALDH1A1 | |
| SCHEMBL8103160 | 0.74 | MAPT (0.62) | GPR174MAPTLMNAGAAALDH1A1 | |
| SCHEMBL8070760 | 0.73 | MAPT (0.50) | GPR174MAPTLMNAGAAALDH1A1 | |
| SCHEMBL16580890 | 0.73 | ALDH1A1 (0.49) | MAPTLMNAGAAALDH1A1KCNH2 | |
| SCHEMBL1425030 | 0.72 | MAPT (0.55) | MAPTLMNAGAAALDH1A1SMN1; SMN2 | |
| SCHEMBL8587625 | 0.72 | HTT (0.44) | MAPTALDH1A1SMN1; SMN2MAPK1BRPF1 | |
| SCHEMBL8074360 | 0.71 | GPR174 (0.45) | GPR174MAPTLMNAGAAALDH1A1 | |
| SCHEMBL6200231 | 0.71 | BRPF1 (0.41) | BRPF1BRD4BRD1BRPF3 | |
| SCHEMBL8074358 | 0.69 | GPR174 (0.48) | GPR174MAPTLMNAGAAALDH1A1 | |
| SCHEMBL6202631 | 0.69 | MAPT (0.39) | MAPTLMNAALDH1A1SMN1; SMN2MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6051570-A | ANTIULCER AGENTS | DR. REDDY'S RESEARCH FOUNDATION (IN) | 2000-04-18 | — | — | US | disclosed |