Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 2/20 | 0.42 |
| ▸ | GRM4 | Q14833 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.38 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | HTT | P42858 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | HTR7 | P34969 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 2/20 | 0.35 |
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8074435 | 0.88 | PPARA (0.41) | PPARAGRM4TSHRLMNAMAPT | |
| SCHEMBL8935797 | 0.85 | PPARA (0.49) | PPARATSHRLMNAMAPTPPARG | |
| SCHEMBL1245341 | 0.85 | PPARA (0.49) | PPARATSHRLMNAMAPTPPARG | |
| Hydrochloric Acid SCHEMBL8074407 | 0.84 | PPARA (0.48) | PPARATSHRLMNAMAPTPPARG | |
| SCHEMBL8083193 | 0.84 | TSHR (0.42) | PPARAGRM4TSHRLMNAMAPT | |
| SCHEMBL8074400 | 0.83 | PIN1 (0.44) | PPARAGRM4TSHRLMNAMEN1 | |
| SCHEMBL8083832 | 0.79 | KMT2A (0.42) | PPARATSHRLMNAAPOBEC3AAPOBEC3G | |
| SCHEMBL8082709 | 0.76 | PPARG (0.56) | PPARATSHRLMNAPPARGMEN1 | |
| SCHEMBL8081953 | 0.76 | PPARA (0.42) | PPARAGRM4TSHRLMNAMAPT | |
| SCHEMBL2884339 | 0.76 | ALDH1A1 (0.52) | PPARATSHRLMNAPPARGALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6063810-A | ENANTIOMORPHS | SYNTHELABO (FR) | 2000-05-16 | — | — | US | disclosed |