Known targets — ChEMBL curated mechanism
CHRM1CHRM2CHRM3CHRM4CHRM5SLC6A2dacAdacBdacCftsImrcAmrcBmrdA
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RECQL | P46063 | 1/20 | 0.52 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | CES2 | O00748 | 1/20 | 0.41 |
| ▸ | CES1 | P23141 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.41 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | CA9 | Q16790 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9003649 | 0.89 | KMT2A (0.59) | RECQLHSD11B1KMT2ANPC1RAB9A | |
| Perchlorate SCHEMBL8752338 | 0.87 | KMT2A (0.53) | RECQLHSD11B1KMT2ANPC1RAB9A | |
| SCHEMBL1095578 | 0.78 | TDP1 (0.54) | RECQLKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL8060330 | 0.77 | HSD11B1 (0.57) | HSD11B1KMT2ANPC1RAB9AMEN1 | |
| Trifluoromethanesulfonic Acid SCHEMBL9626694 | 0.77 | CES1 (0.39) | RECQLHSD11B1KMT2AMEN1ALDH1A1 | |
| SCHEMBL11347502 | 0.76 | CYP3A4 (0.45) | RECQLALDH1A1TDP1LMNACA12 | |
| SCHEMBL9003684 | 0.76 | KMT2A (0.44) | HSD11B1KMT2ANPC1RAB9AMEN1 | |
| Perchlorate SCHEMBL9003671 | 0.75 | TDP1 (0.47) | RECQLKMT2ANPC1RAB9AMEN1 | |
| SCHEMBL11345003 | 0.75 | CYP3A4 (0.44) | RECQLALDH1A1TDP1LMNACA12 | |
| SCHEMBL7133269 | 0.74 | CA12 (0.47) | RECQLKMT2AMEN1ALDH1A1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0665470-B1 | Method for forming a fine pattern | MATSUSHITA ELECTRIC INDUSTRIAL CO LTD (JP) | 2000-08-02 | — | — | EP | disclosed |
| US-5518579-A | SEMICONDUCTORS | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1996-05-21 | — | — | US | disclosed |
| EP-0665470-A2 | Method for forming a fine pattern | MATSUSHITA ELECTRIC INDUSTRIAL CO., LTD. (JP) | 1995-08-02 | — | — | EP | disclosed |