SCHEMBL8075152

SCHEMBL8075152

CC(=O)[C@]1(O)C[C@H](n2cc(C)c(=O)[nH]c2=O)O[C@@H]1COP(O)O

nearest known ligand 0.44

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
TK1 P04183 7/20 0.44
RNASE1 P07998 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6934554 0.93 TK1 (0.45) TK1RNASE1
SCHEMBL551408 0.85 TK1 (0.49) TK1RNASE1
SCHEMBL9753627 0.80 TK1 (0.48) TK1
SCHEMBL8177256 0.77 TK1 (0.34) TK1
SCHEMBL8329365 0.77 LMNA (0.44) TK1
SCHEMBL23032327 0.76 BCHE (0.52) TK1
SCHEMBL25769806 0.76 BCHE (0.52) TK1
SCHEMBL4077432 0.76 TK1 (0.46) TK1RNASE1
SCHEMBL9084280 0.76 TK1 (0.46) TK1
SCHEMBL1827367 0.75 TK1 (0.44) TK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6028182-A Methylphosphonic acid esters, processes for their preparation, and their use HOECHST AKTIENGESELLSCHAFT (DE) 2000-02-22 US disclosed