Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TK1 | P04183 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | ALB | P02768 | 2/20 | 0.49 |
| ▸ | BLM | P54132 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | RNASE1 | P07998 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4077432 | 0.89 | TK1 (0.46) | TK1LMNAALBBLMALDH1A1 | |
| SCHEMBL7780995 | 0.88 | TK1 (0.45) | TK1LMNAALBBLMALDH1A1 | |
| SCHEMBL6374108 | 0.88 | LMNA (0.53) | TK1LMNAADRA1ATSHRPMP22 | |
| SCHEMBL11343250 | 0.88 | TK2 (0.47) | TK1 | |
| SCHEMBL8075152 | 0.85 | TK1 (0.44) | TK1RNASE1 | |
| SCHEMBL8999491 | 0.85 | RNASE1 (0.55) | TK1RNASE1 | |
| SCHEMBL6394877 | 0.85 | LMNA (0.52) | TK1LMNAALBBLMALDH1A1 | |
| SCHEMBL5086587 | 0.85 | LMNA (0.52) | TK1LMNAALBBLMALDH1A1 | |
| SCHEMBL6934554 | 0.84 | TK1 (0.45) | TK1RNASE1 | |
| SCHEMBL23882937 | 0.84 | LMNA (0.51) | TK1LMNAALBBLMALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 68 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59141591-A | — | — | None | — | — | JP | disclosed |
| JP-59141590-A | — | — | None | — | — | JP | disclosed |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | EVONETIX LTD. (GB) | 2021-11-02 | — | — | US | disclosed |
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | SILICON VALLEY BANK | 2021-04-15 | — | — | US | disclosed |
| EP-3609866-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | Evonetix Ltd (GB) | 2020-02-19 | — | — | EP | disclosed |
| WO-2018189546-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | EVONETIX LTD (GB) | 2018-10-18 | — | — | WO | disclosed |
| EP-2580198-B1 | THERMOLABILE 2-(N-2-PYRIDIYL-N-BENZYL)-AMINOETHYLOXYCARBONYL DERIVATIVES AS HYDROXYL FUNCTION PROTECTING AGENTS | INST CHEMII BIOORG POLSKIEJ AKADEMII NAUK (PL) | 2016-08-10 | — | — | EP | disclosed |
| US-8759509-B2 | Way of using thermolabile groups to protect hydroxyl functions and compounds for implementing the procedure | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2014-06-24 | — | — | US | disclosed |
| US-20130085272-A1 | NEW WAY OF USING THERMOLABILE GROUPS TO PROTECT HYDROXYL FUNCTIONS, AND NEW COMPOUNDS FOR IMPLEMENTING THE PROCEDURE | INSTYTUT CHEMII BIOORGANICZNEJ POLSKIEJ AKADEMII NAUK (PL) | 2013-04-04 | — | — | US | disclosed |
| US-8268318-B2 | Polyalkylene oxides having hindered ester-based biodegradable linkers | ENZON PHARMACEUTICALS, INC. (US) | 2012-09-18 | — | — | US | disclosed |
| WO-1992020650-A2 | PHOSPHITE-BORANE COMPOUNDS, AND METHOD OF MAKING AND USING THE SAME | BORON BIOLOGICALS, INC. (US) | 1992-11-26 | — | — | WO | disclosed |
| US-5143907-A | Antitumor and antiinflammatory agents, hypolipidemic activity | BORON BIOLOGICALS, INC. (US) | 1992-09-01 | — | — | US | disclosed |
| US-5138045-A | POLYAMINE CONJUGATED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS (US) | 1992-08-11 | — | — | US | disclosed |
| WO-1992002531-A1 | NOVEL POLYAMINE CONJUGATED OLIGONUCLEOTIDES | ISIS PHARMACEUTICALS, INC. (US) | 1992-02-20 | — | — | WO | disclosed |
| EP-0460045-A1 | NUCLEOSIDE ANALOGUES | UNIVERSITY COLLEGE LONDON (GB) | 1991-12-11 | — | — | EP | disclosed |
| WO-1991008213-A1 | OLIGORIBONUCLOSIDE AND OLIGODEOXYRIBONUCLEOSIDE BORANOPHOSPHATES | BORON BIOLOGICALS, INC. (US) | 1991-06-13 | — | — | WO | disclosed |
| WO-1991004983-A1 | NUCLEOSIDE AND POLYNUCLEOTIDE THIOPHOSPHORAMIDITE AND PHOSPHORODITHIOATE COMPOUNDS AND PROCESSES | UNIVERSITY PATENTS, INC. (US) | 1991-04-18 | — | — | WO | disclosed |
| WO-1990010012-A1 | NUCLEOSIDE ANALOGUES | UNIVERSITY COLLEGE LONDON (GB) | 1990-09-07 | — | — | WO | disclosed |
| JP-S59141590-A | PREPARATION OF AMMONIUM (5-IODO-3-INDOLYL) 5'-THYMIDYLATE | FUJIREBIO INC | 1984-08-14 | — | — | JP | disclosed |
| JP-S59141591-A | PREPARATION OF AMMONIUM (5-IODO-3-INDOLYL) 5'-THYMIDYLATE | FUJIREBIO INC | 1984-08-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210107934-A1 | THERMALLY-CLEAVABLE PROTECTING AND LINKER GROUPS | CTDSP1, RNGTT, SSU72 | TK1 152/4885LMNA 311/4885ALB 3912/4885 |
| US-20130085272-A1 | NEW WAY OF USING THERMOLABILE GROUPS TO PROTECT HYDROXYL FUNCTIONS, AND NEW COMPOUNDS FOR IMPLEMENTING THE PROCEDURE | RNGTT, POLB, UNG | TK1 238/4885LMNA 320/4885ALB 3932/4885 |
| US-11161869-B2 | Thermally-cleavable protecting and linker groups | CTDSP1, RNGTT, SSU72 | TK1 152/4885LMNA 311/4885ALB 3912/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.